ANXA2 gene encodes a calcium-dependent phospholipid binding protein. ANXA2 knockout cells play an important role in various fields such as studying the behavior of cancer cells and removing HCP in the production of recombinant therapeutic proteins.
2021-12-10Wilson's disease (WD) a rare autosomal recessive disorder of copper metabolism, and the pathogenic gene is ATP7B. In order to study the pathogenesis and gene therapy of WD, the cells were gene-edited to construct ATP7B gene knockout or point mutation cell model.
2021-12-10Atg7, which is related to autophagy, is an essential protein for cell degradation and recycling. This sequence is related to the ubiquitin-proteasome system UPS required for the unique development of autophagosome membranes and intracellular fusion. During the initiation of autoph…
2020-09-02Induced pluripotent stem cells (iPS cells) are immature cells generated from adult (mature) cells and have restored their ability to differentiate into any type of cell in the body. Induced pluripotent stem cells (iPS cells) are different from embryonic stem cells (ES cells), whic…
2020-08-20EGFR is a gene on chromosome 7p12, which encodes epidermal growth factor, a transmembrane glycoprotein of the protein kinase superfamily, and a receptor for members of the epidermal growth factor family. The binding of protein to ligand induces receptor dimerization and tyrosine a…
2020-08-18"Knockout CHO Cells0,Stable Cell Lines ,genome editing
2020-08-17Conditional knockout cell line is a technique used to eliminate specific genes in certain tissues, such as the liver. This technique is very useful for studying the role of individual genes in living organisms. It is different from traditional gene knockout technology because it t…
2020-08-10Scientists have developed a continuous knockout cell line technology based on the CRISPR-Cas9 system, including single and multiple (up to three) target gene insertions and knockouts for the purpose of bacterial modification. The CRISPR/Cas system is a kind of prokaryotic immunity…
2020-08-06