Application

ARPE-19, Genome Surgery and Vision Science, A combo for tackling blindness

ARPE-19 cell line has a visually normal karyotype and expresses RPE-specific markers, the retinal pigment epithelium-specific 65kDa protein (RPE65), and cellular retinaldehyde-binding protein (CRALBP), as has been shown at the mRNA and protein levels, respectively.
An ultimate goal of phosphosite genome editing is to developed genomic medicine

An ultimate goal of phosphosite genome editing is to developed genomic medicine Human Genome Project and DNA sequence data obtained from diseased individuals have provided an unprecedented opportunity for understanding genetic components allied with human diseases. Mutations in ca…
CRISPR gene-editing HeLa cells--front fighter of medical breakthroughs

HeLa cell line has contributed to many medical breakthroughs, from research on the effects of zero gravity in outer space and the development of the polio vaccine to the study of leukemia, the AIDS virus, and cancer worldwide.
Gene edited ESCs/iPSCs for regenerative and personalized medicine

Gene edited ESCs/iPSCs for regenerative and personalized medicine Pluripotent stem cells can give rise to all cells and constitute the mature organism. These specialized cells can be cultured in vitro and are referred to as embryonic stem cells (ESCs). ESCs have undergone a great …
CRISPR gene editing MC-3T3 cell line ——A useful tool of bone related research

A useful tool of bone related research -- CRISPR gene editing MC-3T3 cell line MC-3T3 is a model osteogenic cell line derived from newborn mouse calvaria in 1981. This osteogenic cell line retains its capacity to differentiate into osteoblasts and mineralize in vitro, which makes …