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Structures of p53/BCL-2 complex suggest a mechanism for p53 to antagonize BCL-2 activity
IF=16.6
Nature Communications
Author: Hudie Wei, Haolan Wang, Genxin Wang, Lingzhi Qu, Longying Jiang, Shuyan Dai, Xiaojuan Chen, Ye Zhang, Zhuchu Chen, Youjun Li, Ming Guo & Yongheng Chen
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Non-coding small nucleolar RNA SNORD17 promotes the progression of hepatocellular carcinoma through a positive feedback loop upon p53 inactivation
IF=15.8
CELL DEATH AND DIFFERENTIATION
Author: Junnan Liang, Ganxun Li, Jingyu Liao, Zhao Huang, Jingyuan Wen, Yu Wang, Zeyu Chen, Guangzhen Cai, Weiqi Xu, Zeyang Ding, Huifang Liang, Pran K. Datta, Liang Chu, Xiaoping Chen & Bixiang Zhang
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Silica Nanoparticles Trigger Chaperone HSPB8-Assisted Selective Autophagy via TFEB Activation in Hepatocytes
IF=15.2
Small
Author: Ye Zhu 1 2, Yukang Zhang 1 2, Zhuying Fan 1 2, Yuting Fang 1 2, Yucao Zheng 1 2, Yang Li 1 2, Man Yang 1 2, Caixia Guo 1 2, Yanbo Li 1 2, Xianqing Zhou 1 2, Zhiwei Sun 1 2, Ji Wang 1 2
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ZNF432 stimulates PARylation and inhibits DNA resection to balance PARPi sensitivity and resistance
IF=14.9
Nucleic Acids Research
Author: Julia O’Sullivan, Charu Kothari, Marie-Christine Caron, Jean-Philippe Gagné, Zhigang Jin, Louis Nonfoux, Adèle Beneyton, Yan Coulombe, Mélissa Thomas, Nurgul Atalay, X Wei Meng, Larissa Milano, Dominique Jean, François-Michel Boisvert, Scott H Kaufmann, Michael J Hendzel, Jean-Yves Masson, Guy G Poirier
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The extracellular cyclophilin A-integrin β2 complex as a therapeutic target of viral pneumonia
IF=12.4
Molecular Therapy
Author: Xiaoyuan Bai ,Wenxian Yang ,Yuna Zhao,Tongtong Cao,Runshan Lin,Pengtao Jiao,Heqiao Li,Huizi Li,Jie Min,Xiaoxiao Jia,He Zhang,Wenhui Fan,Xiaojuan Jia,Yuhai Bi,Wenjun Liu,Lei Sun
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Peptide-based allosteric inhibitor targets TNFR1 conformationally active region and disables receptor–ligand signaling complex
IF=11.1
Proceedings of the National Academy of Sciences
Author: Jialiu Zeng,Gavin Wen Zhao Loi,Eka Norfaishanty Saipuljumria,Marco Antonio Romero Duránc, Octavio Silva-Garcíac, Jose Manuel Perez-Aguilard , Víctor M. Baizabal-Aguirrec, and Chih Hung Loa,
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